This is something of interest to me. I have no evidence of it, except the fact that if it did happen, and if it only happened within specific host or primary host, it would be missed by observation. Because these microbes carry such complex gene-line variation, it can be hard to recognize mutations, and related phenotypes.
Plus, what about gene sharing? Some microbes are known for this, and some share plasmids which can offer extended genetic characteristics to the microbe.
I will be posting more on this later..........
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To view youtube account my user name is mualfa123 This will enable you to see clips of my microscopic work.