Proteasome and it's role in immunity

It is one direction scientists are taking to review some of the aspects of disease.
One very important mechanism of antigen presentation, is the digestion of said antigen, into small [8-10kDa] peptides which fit well within the Class 1 MHC receptor pocket.
Since everyone has different genes that code for MHC receptor, there is a significant polymorphism that exists here. This is how nature ensures greater diversity among same species, so odds of survival are increased in the face of danger from disease.
If one person cannot handle a solid presentation of antigen because of poor binding properties of antigen, another person may do this extremely well. This individual will have best chance at eliminating dangerous antigens [virus, intracellular disease etc].

The proteasome is a little molecular machine in all eukaryotic cells which digest proteins within the cell for recycling, antigen presentation, or elimination.

I have to make a personal comment on this process. Why can't we grow cells in culture, of people who have ability to digest certain antigens, isolate them, and serve them to a person who has poor ability to digest this particular antigen.
It would stand to reason, the individuals t-cells will pick-up these pre-digested antigens, and have far better chance of making a successful presentation.
Why could we not experiment with the proteasomes of certain frogs or other exotic life forms to evaluate the antigen digestion abilities of their proteasomes, and keep a data base of these records?

Potential for creating unique vaccinations seems promising using this direction.
That was just a personal observation, and maybe it's old news. I have not researched it very far, yet.