I am taking an immunological approach, strategically designed to prompt neurotransmitter shifts in the body, directed at disrupting mast cell stimulation.
This will be attempted by ingesting 120 mg of pseudoephedrine hydrochloride and 7200 mg of ascorbic acid at once before bed.
This is only a preparatory experiment to record physiologic affects.
Pathways of interest are those involve with alpha melanocyte hormone regulation, numerous cytokines and other regulators.
Chemical competition for mast cell receptors is a key goal in this experiment.
By disrupting the status of chronic stimulation of mast cells, I hope to damage the equilibrium, infecting {apicomplexia} parasites are creating with immune functions. I am assuming the parasite is deliberately sequestering the mast cells to control mediators governing other immune factors.
The protocol may not be effective, but observations could be useful.
This is March 15 2009
Day after the experimental drug\vitamin C cocktail;
My symptomolgy dropped by close to 80%! This was completely unexpected, but confirms the hypothesis that mast cells are the central area of concern. This places the disease in awkward direction.
It has been proven the parasitic 'zoites infect these cells in vitro, so elevation of activity with these cells is no surprise. The consequences of sustained amplitude in cell activity and differentiation, is physiologic toxicity. This is now an established fact based on solid scientific evidence.
The next hypothesis is; does the parasite deliberately create a system of survival by using the mast cells and\or other highly specific immune processes to it's advantage?
The fact these parasites cannot live among lactobacteria in vitro, and my digestive system is almost devoid of these types, suggest the mast cell activity kills these bacteria which could be advantageous to the parasite. The epithelial cells are very active producing cryptocidins as well, which might also play a part. It seems these molecules in high abundance, help growth of parasite in vitro. It also has antibiotic effect.
I have noticed high defensin activity in prostatic fluid, and cysts have been observe there [I have seen other unidentified objects of microbial interest there as well].
The next phase of this experiment, is to triple the dosages{per day}, add charcoal and chorophyll to the protocol, and dramatically increase probiotics, and yeast to diet.
I will do prostatic fluid exam in one week. Stool exams will be on going to observe changes in microbiota.
WARNING Do not attempt this experiment. There are dangers associated with cardiac functions in some people.
Date March 17\2009
The experiment has been successful in making a dynamic shift in my overall physiology, symptomology. The symptoms which have been undeviating for many months have shifted.
I think the ascorbic acid has interacted with the pseudoephedrine hydrochloride more than I had expected.
There has been changes in sleeping patterns, and big changes in digestion.
Mood changes are in good territory, indicating hormonal\neurotransmitter adjustment.
These are not subtle changes, and are related to the protocol. Further investigation of these chemical interactions must be elucidated.
Note: I have reduced the pseudoephedrine to 60 mg and ascorbic acid to 500 mg once a day. I have added bentonite and chlorophyll to the protocol as well.
March 18 2009'
The reduced dosage of pseudoephedrine hydrocholide, has allowed homeostasis functions of the body to become stable, and therefore effects of anti-inflammation to wear off. The ascorcic acid, also speeds the metabolic processes of the pseudoephedrine hydrochloride, through the body, and reduces affect.
The impact of infection was not affected, and symptoms are very quick to return.
Therefore, it would seem decreases in mediators from mast cells were either not strong enough to cause differential impact on parasitic factors, or parasite has no intimate reliance on mast cells specifically.
Antigen stimulation, at sub-levels of immune activation are what probably keep symptoms and parasitic infection in balance. ---end of study-----
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Have you tried ascorbic acid plus sea salt? I'm starting slowly, drinking a concoction consisting of:
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Slightly heaping half teaspoon sea salt
Heaping half teaspoon vitamin C powder
100mg potassium capsule contents
Half scoop Ultima Replenisher all-natural sports drink mix, for flavor as much as anything
Filtered water
That's for first thing in the morning. Lemon juice is to help clean the liver. Today I added a midafternoon serving without the lemon juice and sports drink mix. I don't think I'll add a third serving per day.
Interestingly, my excessive thirst is no more excessive and maybe less despite all that salt. I needed to replace salt lost from drinking 2-3L/day of water? Even more interestingly, the whites of my eyes appear to have brightened even more.
I think that the liver and/or kidneys are very important in filtering out whatever this critter is. Elevating the heart rate with cardio workouts helps those filters to do their jobs?
I'm still drinking the two mugs of green tea after breakfast that started brightening the whites of my eyes.
I'm guessing that high doses of ascorbic acid do more than anything else in your protocol? 7 grams seems like a bit much? Parasites don't like salt so, barring side effects, I'll keep that up. I'm not sure the potassium I'm using is needed. Multiple antioxidants seems like the way to go?
I'll wait for your results with charcoal and chlorophyll before I try those.
Large doses of ascorbic acid have the annoying but useful side effect of cleaning out the gut. I've switched to level half teaspoons and will gradually stop this experiment, or at least the ascorbic acid part. My other symptoms seem to have improved but cleaning out the gut tends to do that. It would help of course if I knew what I was doing.
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